RDE Advisors | Senior Full-Stack Engineer | REMOTE (Europe, LatAm, India) | CONTRACT | $4K–6K USD/mo

We're a boutique commercial real estate advisory in NYC building two production web applications: a CRE search platform and a property management platform with QuickBooks integration. Both are live with real users. Stack is Next.js 14, TypeScript, Supabase/Postgres, Prisma, Anthropic Claude API, Mapbox, Vercel + Contabo.

Hiring one senior full-stack engineer to take both products from early-stage to production-mature. You'll work directly with the founder — no engineering managers, no PMs, no committees. 35–40 hrs/week, 6-month minimum, exclusive. Rate is $4,000–5,000 USD/mo for India-based engineers and $5,000–6,000 USD/mo for engineers in Europe or Latin America.

Requirements: 5+ years full-stack, 3+ shipping production web apps, strong Next.js/React + TypeScript, shipped at least one production LLM integration (Claude preferred, OpenAI fine), 2+ hours daily overlap with NYC, available for a 30-min video check-in every weekday at 9:30am ET. This is a product engineering role that calls the Claude API, not an ML/research role.

Non-negotiables: you personally write 100% of the code (no subcontracting, no "my team"), video on for all calls, personal verified GitHub, Hubstaff time tracking, ID check + one prior-client video reference before contract signing.

Apply: https://forms.office.com/Pages/ResponsePage.aspx?id=bw3hQziC...

We respond to qualified applicants within one week. No DMs — please apply through the form.

Turquoise Health is a series C HealthTech startup, spread out remotely across the USA.

We are hiring for full time software engineers for our product engineering team to tackle the black hole of what is now America's healthcare revenue cycle. If you are a high performing full stack engineer who can be collaborative, innovative yet operates with no ego then we want you.

Our tech stack here is as follows: Python, Django, FastAPI, React, Typescript, Vue.Js etc

Engineering Manager, Data Products: https://jobs.ashbyhq.com/turquoise-health/e3b8b4e7-d1a7-4329...

Sr SWE, Consumer- https://jobs.ashbyhq.com/turquoise-health/f0c47e0e-ff1a-480c...

Sr Swe, Contracts-https://jobs.ashbyhq.com/turquoise-health/1d3ec150-1bf0-45df...

Curie | AI Engineer | Hybrid (Chicago), Remote (San Francisco) | Full-time

Curie is a telehealth platform combining clinical expertise with AI to deliver personalized, accessible care — intelligent intake, treatment matching, and AI-powered tools for clinicians. Team includes ex-founders, clinicians, and engineers from Stanford, Harvard, UCLA, Berkeley, and AWS. Well-funded and growing fast.

We're hiring an AI Engineer to own the microservice layer powering our clinical AI: agentic intake workflows, RAG pipelines grounded in medical guidelines, session/memory management for long-running clinical agents, and HIPAA-grade observability and safety guardrails. You'll shape the AI architecture of a healthcare product from the ground up.

Stack: Langgraph, Langfuse, Go, Python, TS, GraphQL, gRPC/Connect-RPC, PostgreSQL, GCP/Vertex AI, AWS Bedrock.

Looking for: 5+ years engineering, meaningful production AI/ML experience, LLMs in production (prompting, structured output, evals), RAG and agentic patterns, comfort across Go + Python + cloud. Bonus: FHIR/HL7, fine-tuning, healthcare AI background, startup experience.

Apply: https://jobs.ashbyhq.com/curie/cea56a9a-d238-4101-a56c-f94a4...

Prosper AI | getprosper.ai | ONSITE Barcelona | Full-time

We build AI phone agents for US healthcare — insurance claims, benefit verification, scheduling. 300K+ calls/month, Series A closed, R&D fully in Barcelona.

Stack: Python, FastAPI, React/TypeScript. Small eng team, fast pace, real ownership.

Hiring for: - Senior Software Engineer: https://jobs.ashbyhq.com/prosper-ai/29fbeb7b-5673-498f-8333-... - Software Engineer: https://jobs.ashbyhq.com/prosper-ai/92f63920-a269-4039-8cf9-...

3–4 days onsite in Eixample. Stock options. ~2 week process.

Questions welcome, feel free to email our freelance recruiter Todora at hello@todora.co

BillionToOne (YC S17, NASDAQ: BLLN) | Menlo Park, CA | Onsite

We're a molecular diagnostics company. YC made a video of us recently: https://www.youtube.com/watch?v=kkv5rZhrLkc.

Our software team creates products that help detect prenatal genetic conditions non-invasively and uncover 50%+ more cancer treatment options. Your code reaches patients and the providers making decisions for them.

Stack: Python, React, TypeScript, AWS, Postgres. We believe in small teams with high ownership.

We're hiring:

- Senior Software Engineer (Prenatal, Oncology, Digital Experiences)

- Senior AI Engineer

- AI Engineering Intern

- Lead UX Designer / Designer

See our engineering specific recruiting page at https://engineering.billiontoone.com/#roles. You can reach out to me directly with a resume at kwu@billiontoone.com.

Colonist | Full-Stack Product Dev | Remote (Eastern Europe / SEA) | Full-time

Colonist (https://colonist.io/) is a multiplayer strategy game with millions of players. We're a small team and you'll own features end-to-end, from backend game logic to polished UI.

You'll work on evolving our game architecture, ensuring cleaner code boundaries and better scalability.

Stack: TypeScript, Node.js, React, CSS, PostgreSQL/SQL. We lean heavily on AI tooling for development.

More details and apply: https://jobs.ashbyhq.com/colonist/109d62c4-52f3-4980-9c49-d3...

Chestnut | Product Engineers (Backend / Full-Stack) | SF + Seattle (Hybrid) | https://jobs.ashbyhq.com/Chestnut

Chestnut builds the systems insurance carriers actually run their distribution business on. We replace spreadsheets, legacy vendor systems, and manual processes with real-time data, deterministic workflows, and AI-assisted tooling.

This is end-to-end product engineering.

You won’t just write APIs. You’ll design schemas, build backend logic, ship UI, deploy to production, and handle the sharp edges that show up with real customers. The problems are messy and state-heavy: payouts that must reconcile with finance, onboarding flows with regulatory constraints, dynamic hierarchies, retries, chargebacks, partial failures.

We care a lot about correctness. These systems move real money and cannot drift.

Stack: Go, TypeScript/React, Postgres, Temporal, Kubernetes, AWS

We use AI heavily in our workflow — for drafting, refactoring, test generation, and exploring solutions. We expect engineers to use it aggressively. We also expect you to understand what it’s doing, spot when it’s wrong, and maintain strong fundamentals. Taste matters.

You’ll likely thrive here if you: - Have 3–6 years building real product systems - Are strong in at least one typed language and comfortable picking up others - Enjoy owning features end-to-end - Think in terms of invariants, edge cases, and failure modes - Like shipping quickly but cleanly - Want to build systems that operate in production, not demos

We’re a small, high-agency team. You’ll have meaningful ownership and direct impact on customers.

Hybrid in SF and Seattle.

Questions or want to sanity-check fit: nick [at] chestnutfi [dot] com

Full-Stack Engineer (Python / React) , Remote

We’re working on building production AI systems , not demos ,focused on real-world workflows, data pipelines, and integrating LLM-based systems into usable products.

Stack: - Python (FastAPI) - React / TypeScript - AWS / PostgreSQL

Work includes: - designing backend systems and APIs - building and scaling LLM workflows (agents, pipelines, RAG) - handling real-world issues like latency, reliability, and hallucination control - integrating AI into product experiences end-to-end

Looking for engineers who: - have built production systems (not just prototypes) - are strong on backend design and data flow - have experience with AI/LLM systems in real use cases

Remote, async-friendly, with some overlap with US timezones preferred.

If interested, apply here: https://lnkd.in/dbiCSZhW

ThreatMark | Security, Machine Learning | REMOTE(World) / Brno, Czech Republic | Equity

ThreatMark protects >50M end users from finacial fraud and saves > $100M every year in losses. We are working with top banks in EU and US to protect their end users. We develop large-behavioral models that recognizes returning users by their mouse movements, keystroke timings and sensoric data (accelerometer, gyroscope).

We detect cyberthreats (e.g. malware, phishing, scraping) by exploiting browsers/sandboxes of devices. We manage ~PB scale of data and provide realtime scoring in milliseconds driving authentication/authorization flow (2nd factor).

Stack: [python, typescript, rust], [redis, postgresql], [aws, terraform] ...

We are looking for exceptional engineers to build with us and be part of the success:

- Backend Engineer [rust, python] - low-latency stream processing engine, rewrite python microservices to rust

- DevOps Engineer (IaaC in AWS)

If you are interested, please email us @ career@threatmark.com with subject "HN Who's Hiring"

If you don't find the right role here or at https://www.threatmark.com/careers/, write us anyway if you believe you can be good fit :)

Krystof Hilar, Co-Founder & CTO

Subsalt (getsubsalt.com) | Senior Product Engineer | Remote (US Only) | Full Time Much of the world's most valuable data — healthcare records, financial transactions, clinical trial data — can't be easily analyzed because it contains sensitive personal information. Today, access to this data is controlled through slow, manual governance processes that can take months to approve. Our goal is to make regulated datasets easy to analyze without exposing the people inside them.

We're looking for an ambitious senior software engineer to join our team. You'll be working directly with enterprise customers to design and extend the core building blocks of our system: scalable data pipelines (Python, Ray, Pytorch), backends (Typescript+Node+Graphql+Rust), agent interfaces (MCP, mem0, ???), and Kubernetes-based customer deployments (Helm, Terraform). The role is customer-facing, the product and mission are really ambitious, and you'll be helping to establish product priorities and company culture on top of your technical contributions.

Would love to chat if this sounds interesting - reach out to jobs at getsubsalt.com and mention HN, include your LinkedIn + Github + resume and briefly describe something you've worked on recently that you're excited about.

More info: https://wellfound.com/jobs/3994817-senior-product-engineer

Integral | Full Stack Developer or Technical PM | Remote (LATAM or US) | $40-90/hr | Contract | https://gointegral.co

Integral is a fractional CTO and AI transformation partnership for scaling businesses ($10M-$100M). We embed with clients as their technology team across strategy, architecture, and hands-on implementation. These are long-term retainer partnerships, not project work. We are a team of 4 today, scaling to 6-8 by the end of 2026.

We’re hiring for two roles:

Full Stack Developer | Remote | Full-time (~40 hrs/week) | LATAM or US

You ship features end-to-end across multiple client projects. Our clients do not have tech departments, so requirements come as business problems, not detailed tickets. You translate “customers need to see order history” into a working feature: data model, API, UI, and deployment.

AI is how we operate. Our team ships faster than teams 3x our size because we use Claude Code, Cursor, and AI-assisted workflows across every phase of development. If you are still writing every line by hand, this is not the right fit. We want developers who have fundamentally changed how they build software with AI.

Stack across clients: Next.js, React, TypeScript, Node.js, Supabase, Shopify, n8n, HubSpot, Vercel. You do not need to know all of these. You do need to pick them up fast.

Technical Project Manager | Remote (US) | Part-time (~25 hrs/week)

You own client relationships and delivery coordination: weekly syncs, Slack, email, ClickUp boards, and scope management. You need to be technically fluent enough to spot a bad estimate and explain trade-offs in business language, but you are not writing code.

An AI-native workflow is required for both roles. “I’ve tried ChatGPT a few times” is not what we’re looking for. We evaluate how you use AI tools daily across your real work.

To apply: email hiring@gointegral.co with which AI tools you use daily, a specific example of how AI changed your workflow, and, for the developer role, a link to something you have shipped. Please confirm you've seen the specified pay range or your application may not be processed.

StraighterLine (straighterline.com) | Staff Software Engineer (Full Stack) | Remote (US Only) | Full Time Our mission is to create opportunities for career advancement through access to affordable education. We are also the market leaders in early childhood (ECE) training and certifications. We are looking for two Staff Engineers to help lead development on next-generation AI-assisted learning platforms.

You will be building modern, API-driven, scalable services and applications with React/Next.js, TypeScript, Node.js, GraphQL, and AWS, using AI-native development practices. You will collaborate on architecture, shared services, internal tooling, and interface design, owning features from concept to production.

Competitive base salary, bonus and benefits (401k match).

Apply here: https://jobs.lever.co/straighterline/36d8f56b-14ac-4a35-af0c... and please mention HN under Additional Information. To get full attention, also send your resume, github, and linkedin profiles to hr at straighterline.com with subject line Hacker News.

Temper | Founding Engineer | SF (In-Person) | $150K–$250K + Equity | https://ontemper.com Every time two companies in the physical economy need to exchange data, someone builds a custom integration by hand. Analysts, engineers, QA. All manual. Every time. Google "EDI" if you haven't. It's wild.

We built AI agents that do the whole thing: gather requirements in plain English, write the integration code, test it, deploy it, fix it when it breaks.

We have paying enterprise customers and more demand than we can keep up with.

You'd be the first engineering hire. Agent orchestration, durable execution runtime, self-healing infra, most of the important architectural decisions haven't been made yet.

The founders built a logistics startup from pre-seed to 400+ people. We've been dealing with broken integrations for years.

TypeScript, Effect, Bun, PostgreSQL, K8s, AWS. Paid work day. Under 2 weeks to offer.

work@ontemper.com, mention HN

Instinct Science | Senior Software Engineer (React Native) | REMOTE (US) | Full-Time | $130K–$160K

Instinct Science is the AI leader in veterinary medicine. We build the industry's first clinical intelligence platform — combining a cloud-native EMR, AI-powered scribing (ScribbleVet), real-time clinical decision support, and Plumb's drug information — in one system that helps veterinary teams work smarter, not harder. We acquired ScribbleVet in early 2026 and are building out its next chapter.

This role is embedded directly in the ScribbleVet product team. You'll own the mobile app used daily by thousands of veterinarians to automate clinical documentation.

WHAT YOU'LL DO: - Build and own cross-platform features end-to-end in React Native (iOS + Android) - Identify and resolve performance bottlenecks — state management, native bridges, CI/CD - Ship real AI-powered features alongside a small, high-output team - Collaborate closely with design, product, and backend engineers

WHAT WE'RE LOOKING FOR: - Deep React Native expertise with production mobile app experience - Strong product instincts and QA discipline — you care about what you ship - Actively using AI coding tools

STACK: React Native, Expo, TypeScript, GraphQL

Apply: https://instinctscience.applytojob.com/apply/4Yj4DavJ6D/Seni...

Goodchat | Full Stack Engineer | Remote (close to CET timezone)

We’ve built a monetization and messaging platform in the creator economy. Small team, fast execution, high ownership.

Remote-first, with occasional in-person meetups. We work hard. Expect high intensity, autonomy, and very little process.

Must-have: Supabase (Postgres, Deno, S3) Strong TypeScript Modern frontend frameworks (preferably SvelteKit) Basic Tailwind Basic Git

Nice-to-have: GitHub Actions zod

Compensation: €100–125K base + equity

Show us: A fullstack app you’ve built (0→1) GitHub profile Resume Why you want to work with us

Apply: hr@goodchat.com

Evolve Robotics | XR Engineer, Full-Stack Engineer, Real-Time Engineer | San Francisco ONSITE | $140-200k + equity | https://EvolveRobotics.com

We let people embody machines from anywhere on the planet. Humanoids, drones, industrial arms -- if it moves, someone in a headset can be inside it, doing real work. You know how people remote into desktops? We do that, but for the physical world.

Team of 5 scaling to 10.

XR Engineer -- Build the interface between human input and robot movement. Hand/body tracking, gaze, controllers, spatial UI. Make teleoperation feel like teleportation, not a laggy video call. Experience with three.js, react-three/fiber and the pmndrs ecosystem is a big plus.

Full-Stack Engineer -- Product verticals end-to-end: data modeling, server routes, UI, real-time sync. Fleet management, operator scheduling, org tooling. TypeScript/React. Experience with sync engines or local-first architectures is a big plus.

Real-Time Engineer -- WebRTC internals, peer-to-peer data channels + video, connection lifecycle management in Go. Sub-frame latency with real consequences -- these are physical machines. If you've worked on real-time media infrastructure and want to apply it to something that actually moves, this is it.

We don't care about your title. We care that you can own a problem space end-to-end, move independently, and ship things that matter.

To apply: go to https://EvolveRobotics.com, find the contact form, and beat the game. If you can't get past Evo, this might not be the role.

ArtCraft | Sr. Frontend Eng | Full-time | Anywhere | Remote

We're building the future of how movies are made. We're a fast growing Greycroft backed startup looking to bring on a talented sr. frontend engineer.

Key Responsibilities:

Work closely with teammates and partners in Engineering, Design, and Marketing to build new features and achieve roadmap goals. We prioritize collaboration and cross-functional partnerships, so you won’t operate in silos. Some efforts you might impact include: Supporting new client-side Media features (e.g. image processing pipelines) Improving the performance of media use cases (such as Image and Video) within the rendering engine End-to-end client support of new codecs/compression algorithms Error handling and network retry logicInterface with the rendering engine in scenarios of image and video rendering Drive guidance, quality, and standards for rendering, and explore opportunities that keep us on the bleeding edge of new capability and advancements. Be a mentor and provide thoughtful feedback.

Required Qualifications: 5+ years of experience as a frontend developer Strong frontend skills with React.js, TypeScript, HTML, threeJS, and CSS

comp: competitive

email michael@storyteller.ai and put a fun fact about you in the subject line.

Comulate | Senior Engineer (3+ YoE) | ONSITE in San Francisco, CA We're automating the $7T insurance industry with AI. Seed stage in terms of headcount (~ 20 people) but Series B in terms of business traction (+ cash-flow positive). We've intentionally stayed under the radar.

- Product has caused customers to literally cry tears of joy

- Experienced eng team from Airbnb / Brex / LiveRamp

- Stack: TS, Postgres, React, GraphQL, and Next.js

Apply here: https://about.comulate.com/careers

Adclear | Senior Fullstack Engineer | London, UK | HYBRID (4 days/week) | Full-Time

We're turning compliance from a bottleneck into a creative advantage for regulated brands. Clients include Monzo, Lloyds, PensionBee, and Plum. Raised £2.6m+ from Outward VC in our first 14 months.

The problem: we run multi-agent AI pipelines that evaluate regulated marketing content in real time. The model landscape moves fast and our architecture has to move with it. You'd own how these systems evolve in production, working directly with the CTO and AI engineers, while also shipping across the full stack.

Stack: TypeScript, React, React Router v7, Tailwind, shadcn/ui | Hono on Cloudflare Workers, Drizzle ORM, PostgreSQL (Neon) | Python, FastAPI, LangChain + LangGraph | GitHub Actions

We're 6 engineers. You'd have real input into architecture, tooling, and how the team operates. We use Cursor, Claude Code and Greptile day-to-day.

£75-95k + equity. Private healthcare, gym budget, hardware budget.

Apply (mention "Hacker News" in your notice period section): https://www.adclear.ai/jobs-seniorengineer

Ploid AI | Barcelona, Spain | REMOTE (preferably hybrid) | Core Team | Full-time

We're building an AI-first bioinformatics platform to empower life science researchers with agentic AI and LLMs. Backed by pre-seed funding, a government grant, and customers from biotech, agrotech, and pharma companies, we're looking for a full-stack engineer to join as a core member.

What we're looking for:

• Strong full-stack experience across Go, TypeScript, and Python (Rust is a plus)

• Hands-on AWS infrastructure work (you've built and maintained production cloud environments)

• Experience with multi-tenant architectures: isolation strategies, auth, data partitioning

• Comfort with AI/ML devops: deploying and orchestrating model-serving pipelines, managing GPU workloads, CI/CD for ML systems

• Willingness to own problems end-to-end, from system design to shipping

Nice-to-haves (not all required): LLM integration, RAG systems, HPC infra, cloud/on-prem hybrid systems

About us: We're a team of engineers and scientists with strong academic and industry backgrounds (ex-BCG, PhD in Plant Biotech and Bioinformatics, Mathematics, M.Sc. AI, PhD in Electrical Engineering). We're committed to building something impactful, technical, and genuinely useful for life science.

Apply: hello@ploid.ai

More about us: https://ploid.ai

We also consider internship requests from strong student candidates for research work.

Thanks to everyone who's reached out through previous HN posts, this community has helped us find amazing people.